Open access
Aug 2026
Eriodictyol regulates LDHB to trigger mitophagy-mediated NLRP3 inflammasome inactivation as a therapeutic strategy for bone loss.
It is confirmed that ERI maintains bone homeostasis by regulating PINK1/Parkin-mediated mitophagy and suppressing NLRP3 inflammasome activation, which may provide a novel natural candidate for the treatment of bone loss-related diseases.
Yi-Yuan Wang, Wen Pu, Yuangang Su et al.
· Pharmacological Research · 0 citations