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It is indicated that CRP and SAP have evolved distinct subcellular localization and regulatory functions, with CRP fine-tuning the NF-κB/TNFα axis and SAP promoting an IL-4-associated response.
Co-immunoprecipitation assay demonstrated that both trFyn and trLck could interact with trZap-70 in HEK-293T cells, providing molecular basis for further study of the TCR signaling and T-cell mediated immunity in golden pompano.
A novel piscidin was identified in largemouth bass that contained an active peptide of 25 aa with an amphipathic helix possessing distinct hydrophobic and positively charged regions, and was significantly up-regulated in spleen from 6 h to 24 h post-lipopolysaccharide (LPS) stimulation.
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