Open access
Aug 2026
Quercetin protects HTR-8/SVneo human trophoblast cells against oxidative stress injury via activating EGFR/PI3K/AKT-NRF2/HO-1 signaling axis
Investigating whether quercetin alleviates H2O2-induced oxidative damage in HTR-8/SVneo trophoblasts via regulating the EGFR/PI3K/AKT-NRF2/HO-1 axis provided a novel mechanism and potential intervention for adverse pregnancy outcomes.
Lu-Jia Liu, Zhixian Ding, Yi-Na Wu et al.
· Frontiers in Pharmacology · 0 citations