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Zhixiang Ding

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Open access Oct 2026

FZD7 drives retinal ferroptosis in diabetic retinopathy via β-catenin-dependent suppression of the DHODH/FSP1 axis.

Inhibition of FZD7 restores endogenous anti-ferroptotic mechanisms and confers retinal protection, establishing FZD7 as a previously unrecognized therapeutic target for diabetic retinopathy.

Jiaojiao Jiang, Liu Zheng, Lu Wang et al. · Journal of Pharmacological S... · 0 citations