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Zhixing Hao

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Review Open access Jul 2026

Cancer Heterogeneity and Cancer Cell Plasticity: Molecular Mechanisms and Precision Therapy

It is argued that drug resistance is critically shaped by cancer cell plasticity, which varies widely among patients and contributes to heterogeneous therapeutic efficacy, and a next‐generation precision oncology paradigm integrating stratified diagnosis, rational combination intervention, and adaptive monitoring is proposed.

Hanwen Hu, Zhixing Hao, Lili Li et al. · 1 citation