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Zhong-Jie Fu

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Open access Sep 2026

Myeloid deficiency of RORα exacerbates lipid dysregulation and laser-induced choroidal neovascularization

Dysregulated lipid and cholesterol metabolism is implicated in the pathogenesis of age-related macular degeneration (AMD), a leading cause of vision loss. Retinoic acid receptor-related orphan receptor alpha (RORα) is a lipid-sensing nuclear receptor genetically associated with neovascular AMD. We investigated the role...

N. Kushwah, Chi-Hsiu Liu, Kiran Bora et al. · 0 citations

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