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Open access Oct 2026

Single-molecule real-time (SMRT) sequencing technology shows advantages in the clinical diagnosis of complex thalassemia

Thalassemia is a hereditary hemolytic anemia caused by pathogenic variants in the α- or β-globin genes, resulting in imbalanced globin chain synthesis. Clinical manifestations vary from asymptomatic carrier states to severe transfusion-dependent anemia. Current routine diagnostic methods in China, gap polymerase ch...

Ning Tang, Shi-Qiang Luo, Xing-Yuan Chen et al. · 0 citations
Open access Oct 2026

Evaluation of HPV E6/E7 mRNA in predicting recurrence after Leep in cervical intraepithelial neoplasia: A study of negative findings

Cervical intraepithelial neoplasia (CIN) is a precursor to cervical cancer, and early detection of residual or recurrent disease is therefore critical for effective management. This study evaluated whether HPV E6/E7 mRNA status predicts recurrence in patients with CIN who underwent loop electrosurgical excision procedu...

Ying-Mei Huang, Jian-Yong Huang, Hong-Mian Jiang et al. · 0 citations

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