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Author

Zhong-Tang Liu

2 papers indexed here

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Open access Sep 2026

Cartilage-targeting engineered probiotic bacterial extracellular vesicles treat osteoarthritis through modulation of matrix homeostasis

Reversing extracellular matrix (ECM) metabolic dysregulation to facilitate cartilage repair represents a key therapeutic strategy for osteoarthritis (OA) treatment. Owing to the avascular nature of joint structures, intra-articular injection is a commonly used clinical administration route. However, the current drug re...

Lu-Yu Niu, Wan-Zhuo Chen, Tong Liu et al. · 0 citations
Open access Sep 2026

An Injectable and Photocrosslinkable Hydrogel Based on Recombinant Human Collagen Type XVII Promotes Osteochondral Regeneration by Activating the TGF β/SMAD Signaling Pathway

This study establishes the pivotal role of collagen type XVII in cartilage regeneration, presenting a promising, minimally invasive strategy with mechanical adaptability and active inductive functionality for functional cartilage defect repair, and expands the cross-tissue application prospects of rhCOL17.

Guan-Ying Yang, Wei Li, Yan-En Wang et al. · 0 citations

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