Safety and cross-neutralization capacity of a Sabin strain-based inactivated polio vaccine: a randomized, double-blind, positive-control clinical trial in 2-month-old infants
The findings suggest that the broad cross-neutralization capacity and favorable safety profile of test-sIPV suggest that it could play a valuable role in global polio eradication strategies, particularly in developing countries transitioning from OPV to affordable IPV-based immunization schedules.