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Zhongxing Jiang

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Open access Sep 2026

Single-cell RNA sequencing uncovers m6A regulator-defined T-cell subpopulations and YTHDF1-HSP90AB1-MYC therapeutic axis in T-cell acute lymphoblastic leukemia.

BACKGROUND N6-methyladenosine (m6A) drives T-cell acute lymphoblastic leukemia (T-ALL); however, its roles in leukemic heterogeneity and tumor microenvironment remodeling unclear. This study characterized N6-methyladenosine regulator-defined subpopulations and YTH N6-methyladenosine RNA binding protein 1 (YTHDF1) in le...

Chao Liu, Wei-Min Wang, Fang Wang et al. · 0 citations

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