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Zhongyan Shan

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Oct 2026

Prunella vulgaris L. ameliorates goiter in Wistar rats is associated with changes in Rap1GAP/CREB3L1/PI3K-AKT signaling pathway.

ETHNOPHARMACOLOGICAL RELEVANCE Prunella vulgaris L. (PV), known as Xia Ku Cao, has traditionally been used in Chinese medicine to dissipate nodules and reduce swelling and is widely used for thyroid disorders. However, its efficacy and mechanisms in iodine-deficiency-induced goiter remain unclear. AIM OF THE STUDY Th...

Guo-Wei Han, Xiao-Qing He, Chen-Yu Zhang et al. · 0 citations
Review Open access Sep 2026

Exposure to nitrogen dioxide and the risk of thyroid disorders: Two nationwide population-based studies in the UK and China.

BACKGROUND Nitrogen dioxide (NO2), a major traffic-related air pollutant, is associated with adverse health effects; however, its relationship with thyroid disorders remains poorly characterized. OBJECTIVE To investigate the associations between long-term NO2 exposure and thyroid-related outcomes in two large populat...

Kai-Jie Yang, Si-Ying Liu, Jie Li et al. · 0 citations
Jul 2026

Association between long-term exposure to environmental coarse particulate matter and the prevalence of thyroid disorders: a cross-sectional study in China.

Long-term PM10 exposure was associated with higher odds of overt hypothyroidism, subclinical hypothyroidism, autoimmune thyroiditis, and TgAb positivity among Chinese adults, suggesting that coarse particulate pollution may be a modifiable environmental factor related to hypothyroidism and thyroid autoimmunity.

Changyuan Liu, Jie Li, Bing-Xin You et al. · 0 citations

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