Zhonnan Xia

Selenomethionine regulates macrophage polarization through mitochondrial dynamics via NF-κB signaling to attenuate sepsis-induced cardiomyopathy.

BACKGROUND Sepsis frequently leads to multiple organ dysfunction, among which sepsis-induced cardiomyopathy (SIC) is a severe complication associated with high mortality and limited targeted therapies. Selenomethionine (SeMet) possesses potent antioxidant and anti-inflammatory properties; however, its role in SIC remai...