Aug 2026
Statins suppress colon tumors by inhibiting KRAS condensates.
It is reported that farnesylation-induced KRAS phase separation drives colon cancer progression and resistance to G12C inhibitors and statins can block this process, suppress tumor growth, and reverse drug resistance.
Zhuangzhuang Yuan, Chenyu Wang, Rong Xiang
· Trends in Molecular Medicine · 0 citations