Zhuo-Cai Wei

Overcoming phototoxicity of sonosensitizers: Curcumin-coordinated iridium(III) complexes for sonodynamic therapy.

Sonodynamic therapy (SDT) holds promise for deep-seated tumors, but most sonosensitizers suffer from severe phototoxicity, requiring patients to avoid light exposure after treatment. Here, we introduce a strategy using natural product curcumin as an auxiliary ligand to construct iridium(III) complexes (Ir1-Ir3). Ir3, f...