Jul 2026
Pathology-Responsive Self-Assembling Hydrogel Enabling Spatiotemporally Controlled Exosome Release and Redox Regulation for Intervertebral Disc Regeneration.
A pathology-adaptive self-assembling hydrogel that exploits dynamically varying catabolic enzyme activity to trigger on-demand delivery of antioxidant molecules and bioactive extracellular vesicles leads to significant structural and functional recovery of the damaged disc, as strongly evidenced in vivo animal studies.
Zhan Gao, Gan Lyu, Qiwei Zhou et al.
· Advances in Materials · 0 citations