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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Zhuo Chen

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2 papers indexed here

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Open access Oct 2026

SPP1⁺ macrophage-derived WNT5A contributes to MMP11⁺ myCAF-mediated matrix remodeling and immunotherapy resistance in lung adenocarcinoma

Lung adenocarcinoma (LUAD) is the leading subtype of non-small cell lung cancer. However, the stromal-immune circuits that coordinate matrix remodeling and immunotherapy resistance in LUAD remain incompletely understood. This study aimed to characterize the stromal-immune interactions associated with LUAD progression a...

Meng-Lei Wang, Peng-Cheng Zhang, Xue-Feng Li et al. · 0 citations
Open access Aug 2026

Clostridium Butyricum and butyrate enhance PD-1 inhibitor therapy in non-small cell lung cancer by regulating the HDAC1/ID2/IL-12R pathway

Highlights • NaB and C. butyricum enhance PD-1 inhibitor activity in NSCLC.• NaB and C. butyricum offer an alternative therapeutic mechanism via HDAC1 inhibition.• NaB cooperates with the PD-1 inhibitors depending on CD8+ T cells in NSCLC.

Zhuo Chen, Meng-Lei Wang, Zhuo-Wen Zhang et al. · 1 citation

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