Author

Zi-Dan Jin

2 papers indexed here

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Open access Oct 2026

GMP-engineered CAR-myeloid cells: overcoming allogeneic barriers in CNS tumors

Chimeric antigen receptor (CAR)-T therapy is limited in solid tumors by poor infiltration and immunosuppression, while myeloid cell translation is hindered by expansion bottlenecks and allogeneic MHC mismatch. Now, Yue et al. establish an expandable granulocyte-monocyte progenitor (GMP) platform that overcomes three lo...

Jia Xu, Zi-Dan Jin · Immunity & Inflammation · 0 citations

Open access Sep 2026

Cross-Serotype Protection of a PstS-YidR Fusion mRNA Vaccine Against Systemic Infection and Endogenous Endophthalmitis Caused by Hypervirulent Klebsiella pneumoniae

Background: Hypervirulent Klebsiella pneumoniae (K. pneumoniae) easily causes bacteremia and liver abscess, and invades the eye via blood circulation to trigger blinding endogenous endophthalmitis. Widespread multidrug resistance limits antibiotic treatment, while traditional capsular polysaccharide vaccines cannot pro...

Jia-Ying Lei, Xin-Xin Lu, Ti-Yun Han et al. · Pathogens · 0 citations