Author

Zi-Fan Wang

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Review Open access Sep 2026

Beyond Exosomes: Biological Properties, Isolation Challenges, and Functional Redefinition of Non-Vesicular Extracellular Nanoparticles (NVEPs)

Extracellular vesicles (EVs) have dominated research on intercellular communication for decades. However, the discovery of exomeres in 2018 revealed that conventional exosome preparations contain large quantities of long-overlooked non-membranous nanoparticles. Additional non-vesicular extracellular nanoparticles (NVEP...

Heng-Xiang Liu, Zi-Shuai Chen, Hai He et al. · Biomolecules · 0 citations

Review Open access Sep 2026

Biomaterial strategies for precision regeneration of the tooth extraction socket: integrating site phenotype, pathological microenvironment, and healing sequence

Alveolar ridge remodeling after tooth extraction is not merely a process of bone defect repair; rather, it is jointly regulated by the anatomical phenotype, pathological microenvironment, surgical procedures, subsequent restorative objectives, and temporal healing sequence of the socket. Existing studies on extraction...

Hai He, Zi-Shuai Chen, Heng-Xiang Liu et al. · Frontiers in Bioengineering... · 0 citations

Open access Aug 2026

Efficient Preparation of pH-Sensitive Core–Shell Drug-Loaded Hydrogel Microcapsules and Their Application in Ulcerative Colitis Treatment

In vitro and in vivo studies demonstrated that this pH-sensitive, core–shell hydrogel microcapsules system provides a promising alternative to existing UC drug delivery systems, linked to precise localization in inflamed tissue, reducing systemic exposure and off-target effects.

Qingqing Xue, Ying-Li Li, Qing Ao et al. · Gels · 1 citation