Open access
Oct 2026
DeCTCF: Decoding CTCF binding sequences by leveraging predicted epigenomic features
CTCF is a key architectural protein with diverse roles in genome organization and gene regulation, yet how it achieves these roles in different contexts remains unclear. Pretrained sequence-based models such as Sei provide predicted epigenomic features that can be used in downstream analyses of regulatory elements. Her...
Lu Chai, Jie Gao, Ting Guo et al.
· PLoS Computational Biology · 0 citations