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Zi-Hao Zhu

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Open access Sep 2026

Erythropoiesis-stimulating agent hyporesponsiveness in chronic kidney disease: mechanistic insights and emerging precision approaches

Erythropoiesis-stimulating agents (ESAs) remain a cornerstone of anemia management in chronic kidney disease (CKD). However, some patients show an inadequate hemoglobin response despite appropriate or increasing ESA exposure. ESA hyporesponsiveness is clinically important because persistent dose escalation may prov...

Hai-Feng Zhang, Zi-Hao Zhu, Xue-Xun Chen et al. · 0 citations

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