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Zi-He Rao

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Open access Oct 2026

Recognition and mechanism of M. tuberculosis cell wall galactan transport

Mycobacterial-derived lipid-linked galactan (LLG) is an essential component of the Mycobacterial tuberculosis (Mtb) cell wall core arabinogalactan (AG), a well-established virulence factor and target of anti-tubercular drugs. Cross-membrane translocation of LLG is energetically unfavorable and is therefore catalyzed by...

Chuan-Cun Wei, Katherine A. Abrahams, Violetta Krisilia et al. · 0 citations
Open access Jul 2026

A dual-receptor checkpoint primes enterovirus D68 for respiratory cell entry

Cryo-EM structures of historical and contemporary AFM-associated EV-D68 strains, together with their complexes bound to the third extracellular loop of MFSD6, reveal a glycan-mediated dual-lock mechanism that may enhance receptor specificity, prevent premature uncoating, and ensure productive infection only upon engage...

Shengjian Liang, Hao-Ran Guo, Zhili Xu et al. · 0 citations

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