Open access
Sep 2026
Multi-omics and machine learning reveal LYZ and ISG15 as diagnostic and therapeutic targets in autoimmune-mediated chronic kidney disease
Background CKD represents a substantial worldwide health challenge, defined by the gradual development of tubulointerstitial fibrosis and reduced renal performance. Autoimmune-mediated factors are central to this pathological process, yet early diagnostic biomarkers and specific therapeutic targets are scarce. The obje...
Haofeng Zheng, Jie-Yi Dong, Qing-Fu Dai et al.
· Frontiers in Immunology · 0 citations