Skeletal muscle repair after injury depends on a tightly coordinated cascade of inflammatory and regenerative responses. Damage-associated molecular patterns (DAMPs) link tissue damage to innate immune activation, but their effects are highly context dependent. This review summarizes the major cellular sources of DAMPs...
Zi-Hui Gao, Xia Li, Ya-Nan Ji et al.· Biochemical Pharmacology· 0 citations
The molecular mechanisms underlying major cell death pathways are summarized and their context-dependent roles in skeletal muscle physiology are discussed, including development, adaptation, regeneration, and aging, as well as in disease progression.
Jiahuan Gong, Hong-Yi Xu, Yun-Tian Shen et al.· European Journal of Pharmaco...· 4 citations
BACKGROUND AND PURPOSE
The molecular mechanisms underlying denervation-induced muscle atrophy remain incompletely understood, and effective therapeutic interventions are currently lacking. Tectorigenin (TG), a natural isoflavonoid, has demonstrated antioxidant and metabolic regulatory activities. This study investigate...
Boya Liu, Fei Xue, Xingxing Fang et al.· British Journal of Pharmacol...· 0 citations
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