Author

Zi-Jia Leng

2 papers indexed here

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Open access Sep 2026

Renal tissue microbiota and metabolite profiling reveal dysregulated signatures in diabetic kidney disease

Introduction Diabetic kidney disease (DKD) has become the main cause of end-stage renal disease in China. Mounting evidence links microecological disorders to DKD progression. However, the composition and the functional characteristics of the renal microecology in DKD patients remain poorly defined. This study characte...

Na Zhao, Zi-Jia Leng, Qi-Qi Li et al. · Frontiers in Microbiology · 0 citations

Review Aug 2026

Mitochondria-centered signalling in pulmonary hypertension: From metabolic reprogramming to vascular remodeling and right ventricular failure.

Pulmonary hypertension (PH) is a progressive cardiopulmonary disorder characterized by pulmonary vascular remodeling, increased pulmonary vascular resistance, and right ventricular failure. Beyond its bioenergetic function, mitochondria act as signalling hubs that integrate metabolic flux, redox homeostasis, calcium ha...

Meng-Jie Zhang, Si-Qin Peng, Na Liang et al. · Cellular Signalling · 0 citations