Zi-Jun Meng

Human CD46 humanized mice reveal interferon associated pulmonary immune remodeling during human adenovirus type 7 lung infection

Human adenovirus type 7(HAdV-7) is a major cause of severe pediatric pneumonia, but the mechanisms linking viral infection to pulmonary immune remodeling and lung pathology remain incompletely understood. Progress has been limited by the lack of physiologically relevant animal models that recapitulate human suscept...