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Author

Zi-Kun Xie

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2 papers indexed here

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Open access Sep 2026

Chaenomeles speciosa-derived extracellular vesicles accelerate fracture healing via orchestrating immuno-angiogenic coupling

Purpose Fracture nonunion remains a major orthopaedic challenge, and dysregulation of the bone immune microenvironment is increasingly recognized as a key pathological driver. Chaenomeles speciosa is a medicinal plant with documented anti-inflammatory properties, making it a promising candidate for immune-modulatory th...

Jing-Xiang Chen, Kai-Han Zhuang, Yufei Wang et al. · 0 citations
Open access Sep 2026

Single cell multi-omics guided hydrogel enables closed-loop therapy for renal osteodystrophy

Fracture repair in renal osteodystrophy remains challenging because impaired bone quality compromises fixation stability, while current systemic therapies regulating bone metabolism do not sufficiently address the disease-specific mechanisms underlying defective repair. An integrated strategy combining early fracture s...

Lei Fan, Ke-Nan Sun, Fei-Ping Xia et al. · 0 citations

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