Review
Open access
Sep 2026
From mitochondria to innate immunity: The mtDNA-driven cGAS/STING-NLRP3 cascade and its therapeutic implications in neurodegenerative diseases (Review)
A modular assessment framework was proposed across the ‘input-chronicity-amplification’ layers and the potential of mtDNA-cGAS/STING-NLRP3 axis-informed stratified diagnosis and treatment was discussed.
Hui Liu, Yao Zhang, Zi-Liang Zhuo et al.
· Experimental and Therapeutic... · 0 citations