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Preprint Oct 2026

Mutual Information in High-Dimensional Neural Coding

Estimating mutual information in large neural populations is limited by the exponential growth of possible neural response patterns. Here we apply a Monte Carlo framework to make this problem tractable by sampling from a conditionally independent population model fit from single-neuron responses. The estimator accurate...

Zi-Mo Li, Yuxuan Tian, Matthew P. Leighton et al. · 0 citations

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