Review
Open access
Sep 2026
The plasticity and metabolic reprogramming of macrophage in ulcerative colitis
Macrophages exhibit phenotypic plasticity, which plays a role in driving tissue injury and promoting mucosal repair in ulcerative colitis (UC). Intestinal macrophages originate from both embryo-derived resident cells and circulating monocytes. Macrophage polarization influences inflammatory responses and is regulated b...
Yi Zhang, Ding-Quan Yang, Jun-Nan Jiang et al.
· Frontiers in Immunology · 0 citations