Zi-Qiang Chen

Targeting Tryptophan Metabolism in Cardiovascular Disease: From Immune-metabolic Crosstalk to Precision Therapy.

Host-microbiota co-metabolism of tryptophan is increasingly recognized as a critical nexus linking diet, gut microbiota, immune function, serving as a core regulatory network governing cardiovascular function and systemic homeostasis. Its catabolism in vivo mainly proceeds through three distinct pathways: the kynurenin...