Author

Zi-Sen Zhang

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Open access Sep 2026

Esomeprazole inhibits EGF-induced invasion and migration of gastric cancer cells

Background Gastric cancer (GC) is one of the most prevalent and lethal malignancies worldwide, with invasion and metastasis being the key factors contributing to its poor prognosis and high mortality rates. Epidermal growth factor (EGF)-induced activation of EGFR and downstream AKT/mTOR signaling plays a central role i...

Fang-Fang Huang, Jin-Feng Du, Xuan-Ruo Zhang et al. · PeerJ · 0 citations

Review Open access Jul 2026

Tumor-associated fibrosis plays a role in cellular immunity across human diseases.

This review summarizes current understanding of the cellular and molecular drivers of fibrotic tumor stroma, highlighting heterogeneous cancer-associated fibroblast (CAF) types, and provides a comprehensive framework for understanding how tumor-associated fibrosis regulates cellular immunity across cancers.

Meng-Ru Tian, Meng-Yu Lian, Li-Hao Zheng et al. · Biomedicine & pharmacotherap... · 1 citation