Bone defects remain a major clinical challenge, creating a need for biomaterials that can simultaneously support osteogenesis, angiogenesis, and immune regulation. Here, we developed lactoferrin (Lf)-loaded mineralized alginate microspheres with integrated osteogenic, angiogenic, and immunomodulatory functions and ev...
Jie Wang, Zi-Wei Liang, Zong-Yi Li et al.· Regenerative Biomaterials· 0 citations
Diabetic wound healing is severely impaired by four core pathological barriers-persistent hyperglycemia, excessive inflammation, bacterial infection, and deficient wound contraction. Herein, we developed a near-infrared (NIR)-responsive antibacterial hydrogel composed of poly(N-isopropylacrylamide), sodium alginate, gr...
Hai-Liang Pei, Tao Xu, Yu Cao et al.· Colloids and Surfaces B: Bio...· 0 citations
Electrospray injection is utilized to prepare ALG-BP composite microspheres encapsulating MC3T3-E1 cells, showing that ALG-BP microspheres had no effect on the activity of MC3T3-E1 cells, while ALG-BP@MC3T3-E1 microspheres exhibited excellent bone healing promotion and osteoporosis inhibition capabilities, significantl...
Yu-Li Fan, Zongyi Li, Xuanyu Liu et al.· Frontiers of Materials Scien...· 0 citations
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