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Zixiong Guo

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Open access Jul 2026

A synthetic virus-like assembly unlocks dual-antigen presentation for broad-spectrum anti-SARS-CoV-2 immunity

This characterized virion-mimetic structural vaccine not only induces the production of high-efficiency antibodies against both the spike and N proteins but also elicits robust S1-specific and N-specific CTL responses in animal models, creating an optimal microenvironment for eliciting potent and broad-spectrum adaptive immune responses.

Jingjing Zhang, Fen Zeng, Yanmei Li et al. · 0 citations