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Effect of moderate-intensity aerobic exercise on early oxidative stress and muscle atrophy in SAMP8 mice through modulation of the DAO/SRR and Nrf2/Keap1 pathways.
It is suggested that moderate-intensity aerobic exercise alleviates early oxidative stress and muscle atrophy by inhibiting the pro-oxidant DAO/SRR pathway and activating the Nrf2/Keap1 antioxidant axis, thereby providing evidence for the molecular mechanisms underlying the attenuation of age-related skeletal muscle de...