This review systematically summarizes the key applications of multiomics technologies in AL amyloidosis research, evaluates recent advances, and provides an analysis of current limitations and challenges.
Zi-Xuan Zhang, Ziru Huang, Hao-Xian Tang et al.· Medicine Bulletin· 0 citations
INTRODUCTION
B-type natriuretic peptide (BNP) is widely used to diagnose and assess heart failure prognosis. However, its effects on pathological cardiomyocyte hypertrophy and the underlying mechanisms remain largely unexplored.
METHODS
Here, we report the use of isoproterenol (ISO)-induced cardiomyocyte hypertrophy...
Changchun Wu, Yaqing Wang, Zixuan Zhang et al.· Current Drug Targets· 0 citations
This review compiles the data resources related to polyreactive antibodies and places a particular emphasis on computational models for predicting antibody polyreactivity, which includes empirical models based on physicochemical properties, traditional machine learning models, deep learning networks, and protein langua...
Haoxian Tang, Zixuan Zhang, Wenzhi Li et al.· Computational Biomedicine· 0 citations
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