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Author

Zi-Yan Zhou

2 papers indexed here

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Open access Oct 2026

Sequence-specific and programmable catalytic degradation of extracellular microRNAs by membrane-anchored DNA nanomachines

Extracellular microRNAs (miRNAs) contribute to metastasis through communication between tumour cells and their microenvironment, yet their sustained, sequence-selective depletion remains challenging. Here we report Programmable RNA-Intercepting Molecular Eraser (PRIME), a membrane-anchored DNA nanomachine that organize...

Zi-Yan Zhou, Ling-Hao Zhang, Xiao-Wei Wang et al. · 0 citations
Open access Aug 2026

Direct visualization of RNA virus and evaluation of drug effect in living cells by catalytically transformable DNA cube

In situ visualization of viral RNA in living cells is critical for understanding infection dynamics and evaluating antiviral responses, yet offline methods such as polymerase chain reaction are incompatible with real-time analysis. Here, a CAtalytically Transformable DNA Cube (CAT-Cube) is presented as a structurally s...

Jiajia Liu, Qimin Yan, Hongbo Qin et al. · 0 citations

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