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Author

Zi-Yi Wang

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Oct 2026

Hollow copper sulfide nanomedicines functionalized with metal polyphenol network for self-augmenting chemodynamic and photothermal therapy.

Chemodynamic therapy (CDT) holds promise for tumor treatment but is limited by insufficient endogenous hydrogen peroxide (H₂O₂) and slow Fe3⁺/Fe2⁺ cycling in the tumor microenvironment (TME). Herein, we report a self-augmenting nanoplatform (CPT@HCuS-TF) by loading camptothecin (CPT) into hollow copper sulfide (HCuS) n...

Jian-Wen Wei, Xiao-Rui Yuan, Hui-Min Xu et al. · 0 citations
Review Jul 2026

Microglial immunometabolic reprogramming in Alzheimer's disease: From mitochondrial dysfunction and redox imbalance to NLRP3 inflammasome-driven neuroinflammation

A stage-dependent mitochondrial dysfunction–redox imbalance–NLRP3 inflammasome axis provides a testable stage-dependent framework for interpreting chronic, self-amplifying neuroinflammation in AD and may inform biomarker-guided, combinatorial therapeutic strategies.

Si-Yu Li, Jun-Tao Jin, Ying-Ying Liu et al. · 1 citation

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