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Sep 2026

Molecular identification of NF-κB subunit RelA in Manila clam (Ruditapes philippinarum) and its regulatory role in inflammatory response during Vibrio parahaemolyticus infection.

Results demonstrate that RpRelA, as a core NF-κB subunit, positively regulates the inflammatory response during V. parahaemolyticus infection in Manila clam, and provide new insights into the immune regulatory mechanism of bivalves against bacterial infection.

Hao-Dong Feng, Tian Yu, Jia-Xi Liang et al. · 0 citations
Jul 2026

Toll-like receptor 2 (TLR2) functions as a key regulator of inflammatory responses to Vibrio parahaemolyticus infection in the Manila clam (Ruditapes philippinarum).

Findings indicate that RpTLR2 acts as a positive regulator of V. parahaemolyticus-induced inflammatory responses and improve understanding of TLR2-mediated innate immunity in mollusks and provide a molecular basis for studying host-pathogen interactions in bivalves.

Jia-Xi Liang, Tian Yu, Hao-Dong Feng et al. · 0 citations

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