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The analysis separates fine-scale comparisons from the regional information needed to allocate their samples at low regret, which separates fine-scale comparisons from the regional information needed to allocate their samples at low regret.
It is shown that LSD1 knockdown has opposing, subtype-specific effects on chemotherapeutic responses: it sensitized RSK-subtype cells to chemotherapy but induced resistance in KRAS-subtype cells, revealing mitochondrial dysfunction and defective mitophagy as hallmarks distinguishing KRAS- from RSK-subtype PDAC.
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