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Jul 2026

The Multifaceted Roles of the Hippo-Yes-Associated Protein (YAP)/Transcriptional Coactivator with a PDZ-Binding Motif Pathway in Regulating the Tumor Microenvironment.

This work discusses recent advances in understanding how this pathway modulates the immune landscape, cancer-associated fibroblasts, and tumor vasculature and outlines how YAP/TAZ drives fibroblast activation, matrix stiffening, and promotes cancer-associated fibrosis.

Zihao Sui, Ting Wang, Chunling Yi · 0 citations