Dual-targeting poly(2-oxazoline)-coated porous silicon nanoparticles for improving osteosarcoma therapy.
Osteosarcoma is the most prevalent malignant bone tumor in children and adolescents. Current treatment of this aggressive tumor with surgery and chemotherapy is hindered by the non-selectivity of chemotherapeutics, leading to severe toxicity and poor outcomes. This urgent clinical challenge necessitates the need for ta...