Review
Open access
Sep 2026
Clinical immunogenicity in rAAV gene therapy: Insights and implications
Recombinant adeno-associated viruses (rAAV) provide prolonged therapeutic protein expression in multiple target organs after single administration, delivering significant clinical benefits with a well-characterized safety profile, and can be further supported by active immune management strategies. Systemic rAAV gene t...
Nitish Gulve, Mariana Bego, Hitesh Gandhi et al.
· Molecular therapy. Advances · 0 citations