Author

Ziwei Chen

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Open access Aug 2026

Spatial multi-omics analysis reveals vimentinhigh macrophages–endothelial cells niche shapes CAFs heterogeneity in colorectal cancer metastasis

A site-specific regulatory mechanism of the macrophage-endothelial niche is revealed, offering a novel and clinically significant biomarker for CRC prognosis.

Mingzhou Li, Bingyu Xu, Jieqiong Wu et al. · bioRxiv · 0 citations

Review Open access Aug 2026

XBP1 signaling from tumor metabolic stress to myeloid driven immunotherapy resistance (Review)

Targeting XBP1 may enhance the efficacy of existing therapies, particularly immune checkpoint blockade, by alleviating MDSC-mediated immunosuppression, offering a novel paradigm for understanding and reversing tumor immune escape.

Ziwei Chen, Jiaqi Wu, Wen-Xi Liu et al. · International Journal of Mol... · 0 citations