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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Zixin Deng

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3 papers indexed here

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Oct 2026

A Radical Addition–Diradical Coupling Switch Unifies Cytochrome P450-Catalyzed Diketopiperazine Dimerization

Cytochrome P450 dimerases generate the remarkable structural diversity of dimeric diketopiperazine (DKP) natural products through highly selective intermolecular radical-mediated reactions. Although radical addition mechanisms have been established for most bacterial DKP dimerization modes, the molecular basis underl...

Ye-Qing Du, Tai-Ping Zhou, Wen-Ya Tian et al. · 0 citations
Open access Aug 2026

An N-acetylated daropeptide modulates nematode development.

Unlike the antimicrobial darobactin, aphotorhaptin A appears to lack antibacterial activity but modulates nematode development, and this activity requires the ether crosslink and the N-terminal acetyl group in the hexapeptide scaffold.

Suze Ma, Ru Li, Xiang-Yang Gao et al. · 0 citations
Aug 2026

Iterative Enoyl Reduction by a FabV-Family Enzyme Expands the Chemical Landscape of Discrete Polyketide Synthases.

PbrC16, a FabV-family ER from a manumycin-type biosynthetic gene cluster (BGC) in Peterkaempfera bronchialis is characterized and reveals the molecular basis for its exceptional substrate promiscuity and versatile acyl carrier protein (ACP) recognition.

Yan Gao, Kai Jiang, Yu-Han Dai et al. · 0 citations

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