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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Zonghao Cheng

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Review Open access Jul 2026

From Traditional Protein Engineering to AI-Driven Design: Principles, Methods, and Applications

This paper focuses on protein structure prediction tools represented by AlphaFold, generative models such as RFdiffusion and ProteinMPNN, and the de novo protein design methods driven by these tools, and analyzes the progress of artificial intelligence in protein design and optimization.

Zonghao Cheng · 0 citations