Zongqiang Li

Catalytic and inhibitory architecture of comammox ammonia monooxygenase

Complete ammonia oxidizers (comammox) are widespread nitrifiers that can dominate ammonia oxidation in diverse environments by efficiently converting ammonia to nitrate within a single cell, yet the molecular basis distinguishing their ammonia monooxygenase (AMO) from those of canonical bacterial AMO remains unresolved...

Structural basis of nucleotide-dependent conformational switching of a CBS-family protein on the archaeal 50S ribosome.

Structural basis of cooperative neutralization of the PldB toxin by immunity proteins in Pseudomonas aeruginosa.

PldB, a type VI secretion system-dependent phospholipase D (PLD) effector secreted by multidrug-resistant Pseudomonas aeruginosa, alters host cell membrane permeability and facilitates pathogen internalization. Its cytotoxic activity is neutralized by three cognate immunity proteins-PA5086, PA5087, and PA5088-which pro...