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Zsófia Kutilová

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Open access Oct 2026

Elevenostat Is an HDAC6/Class I-Biased Multi-HDAC Inhibitor Rather than an HDAC11-Selective Chemical Probe.

Histone deacetylase 11 (HDAC11) is a lysine defatty-acylase with emerging roles in immunity, metabolism, and disease, creating a need for rigorously validated isoform-selective inhibitors. Elevenostat/JB3-22 has been used as an HDAC11 inhibitor, but its HDAC isoform selectivity has remained insufficiently defined. Here...

M. Vošahlíková, Zsófia Kutilová, Júlia Kudláčová et al. · 0 citations

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