Author

Zsu-Zsu Chen

2 papers indexed here

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Open access Aug 2026

Genetic drivers of protein changes over time: Findings, considerations, and approaches in TOPMed cohorts and UK Biobank

Age is a major risk factor for many diseases, but the biological processes driving aging are heterogeneous across individuals. Efforts to untangle differences between chronological and biological age have focused on identifying age-associated markers, such as ’omics clocks. Many ’omics features, including proteins, are...

M. Gillman, H. Chen, A. Howard et al. · bioRxiv · 0 citations

Jul 2026

Proteomic signatures of loss of glycemic control in youth-onset type 2 diabetes in the TODAY study.

CONTEXT Youth-onset type 2 diabetes (T2D) is characterized by accelerated β-cell decline and early treatment failure, and there is an urgent need to improve the understanding of molecular drivers of loss of glycemic control (LOGC). OBJECTIVE To identify multiprotein signatures associated with loss of glycemic control...

K. Tommerdahl, Kristen R Miller, Jian-Jun Liu et al. · Journal of Clinical Endocrin... · 0 citations