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Zu-Guo Zheng

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Open access Sep 2026

Astragaloside IV improves MASLD via GCN5-LXRα/SREBP1c signaling pathway-mediated hepatic de novo lipogenesis

Astragaloside IV (AS-IV), a bioactive saponin from Astragalus membranaceus, shows promise for treating metabolic dysfunction-associated steatotic liver disease (MASLD), though its mechanisms remain unclear. This study aimed to elucidate how AS-IV alleviates hepatic steatosis, specifically investigating its epigenetic r...

Hui-Mei Liang, Yin-Yue Xu, Kun Miao et al. · 0 citations
Aug 2026

High-Dimensional SERS Mapping of Single Circulating Tumor Cells Deciphers the Phenotypic Landscape and Stratifies Metastatic Risk in Pancreatic Cancer.

Applying PRISM to CTCs from pancreatic cancer patients, a novel data analysis framework is introduced, including a 'Metastasis Potential Score' (MPS), to translate high-dimensional spectral data into a clinically relevant metric for risk stratification.

Yanrong Wen, Mengxiang Liu, Chun-Hui Liu et al. · 0 citations

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