Zuo-Jun Huang

Prediction of the clinical outcomes of imipenem and meropenem in patients with treatment-associated AKI and death via machine learning models combined with pharmacokinetic parameters: A retrospective cohort study

Objective The present study aimed to develop and evaluate machine learning-based predictive models for acute kidney injury (AKI) and all-cause mortality in patients treated with imipenem or meropenem, integrating pharmacokinetic (PK) parameters with routine clinical features. Methods A total of 235 patients who receive...